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Invitrogen™ CENPA Monoclonal Antibody (5A7-2E11), FITC
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Catalog No. PIMA545298
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100 μg
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PIMA545298 100 μg
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Catalog No. PIMA545298 Supplier Invitrogen™ Supplier No. MA545298
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Description

Mouse Monoclonal Antibody

1 μg/mL of MA5-45298 was sufficient for detection of CENPA in 20 μg of U2OS cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 18kDa. Recognizes Human CENP-A.

Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CENPA
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 5A7-2E11
Concentration 1 mg/mL
Conjugate FITC
Formulation PBS, 9.1mM sodium bicarbonate with 640.91mM DMSO, 136.36mM ethanolamine and no preservative
Gene Cenpa
Gene Accession No. P49450
Gene Alias CenH3; CENP A; CENPA; CENP-A; Centromere autoantigen A; centromere protein A; centromere protein A, 17kDa; centromere-specific histone; ggCENP-A; histone H3-like centromeric protein A; RGD1563607
Gene Symbols Cenpa
Host Species Mouse
Immunogen Synthetic peptide corresponding to a portion of human CENP-A.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1058
Target Species Human
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

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