Invitrogen™ CENPF Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5144905

Catalog No. FEPA5144905

Description

Immunogen sequence: SCWKSENEKL LTQMESEKEN LQSKINHLET CLKTQQIKSH EYNERVRTLE MDRENLSVEI RNLHNVLDSK SVEVETQKLA YMELQQKAEF SDQKHQKEIE NMCLKTSQLT GQVEDLEHKL QLLSNEIMDK DRCYQDLHAE YE Antigen sequence identity: Mouse 69%; Rat 73%.

This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitosis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease.

Specifications

• Antigen: CENPF
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CENPF
• Gene Alias: 6530404A22Rik; AH antigen; AI325968; cell-cycle-dependent 350K nuclear protein; CENF; CENPF; CENP-F; CENP-F kinetochore protein; centromere autoantigen F; centromere protein F; centromere protein F, (mitosin); centromere protein F, 350/400ka (mitosin); centromere protein F, 350/400kDa (mitosin); CILD31; hcp-1; im:7140452; im:7144238; im:7154719; im:7156761; kinetochore protein CENPF; Lek1; leucine, glutamic acid, lysine family 1 protein; mitosin; PRO1779; RP11-262H5.1; si:ch211-152h14.2; STROMS
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1063
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid
• Isotype: IgG

• Applications: Immunocytochemistry
• Concentration: 0.7 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P49454
• Gene Symbols: CENPF
• Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 620-761. Recombinant protein control fragment (Product #RP-110098).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Format: Liquid