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Invitrogen™ CENPH Monoclonal Antibody (1F7)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA522523
Description
Peptide Sequence: MEEQPQMQDA DEPADSGGEG RAGGPPQVAG AQAACSEDRM TLLLRLRAQT KQQLLEYKSM VDASEEKTPE QIMQEKQIEA KIEDLENEIE EVKVAFEIKK LALDRMRLST ALKKNLEKIS RQSSVLMDNM KHLLELNKLI MKSQQESWDL EEKLLDIRKK RLQLKQASES KLLEIQTEKN KQKIDLDSME NSERIKIIRQ NLQMEIKITT VIQHVFQNLI LGSKVNWAED PALKEIVLQL EKNVDMM.
Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.
Specifications
CENPH | |
Monoclonal | |
0.2-1.0 mg/mL | |
PBS with no preservative; pH 7.4 | |
Q9H3R5 | |
CENPH | |
CENPH (AAH12024, 1 a.a. ~ 247 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG2a κ |
ELISA, Western Blot | |
1F7 | |
Unconjugated | |
CENPH | |
1700021I11Rik; 2410018A12Rik; 2610042E16Rik; 2810046K12Rik; AU044255; CENPH; CENP-H; centromere autoantigen H; centromere protein H; Enp; ICEN35; Interphase centromere complex protein 35; kinetochore protein CENP-H; LOC681185; similar to centromere autoantigen H | |
Mouse | |
Affinity Chromatography | |
RUO | |
64946 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
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