Invitrogen™ CENPH Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103490

Catalog No. PIPA5103490

Description

Antibody detects endogenous levels of total CENPH.

Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.

Specifications

• Antigen: CENPH
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CENPH
• Gene Alias: 1700021I11Rik; 2410018A12Rik; 2610042E16Rik; 2810046K12Rik; AU044255; CENPH; CENP-H; centromere autoantigen H; centromere protein H; Enp; ICEN35; Interphase centromere complex protein 35; kinetochore protein CENP-H; LOC681185; similar to centromere autoantigen H
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64946
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9H3R5
• Gene Symbols: CENPH
• Immunogen: A synthesized peptide derived from human CENPH(Accession Q9H3R5), corresponding to amino acid residues M1-D38.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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