Invitrogen™ CENPJ Monoclonal Antibody (1A5)

Catalog No.	Quantity
PIMA522212	50 μg

Catalog No. PIMA522212 Supplier Invitrogen™ Supplier No. MA522212

Description

Mouse Monoclonal Antibody

Peptide Sequence: KYTTAARTFP DKKEREEIQT LKQQIADLRE DLKRKETKWS STHSRLRSQI QMLVRENTDL REEIKVMERF RLDAWKRAEA IESSLEVEKK DKLANTSVRF QNSQISSGTQ.

This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation.

Specifications

• Antigen: CENPJ
• Applications: ELISA, Immunoprecipitation, Western Blot
• Classification: Monoclonal
• Clone: 1A5
• Concentration: 0.2-1.0 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative; pH 7.4
• Gene: CENPJ
• Gene Accession No.: Q9HC77
• Gene Alias: 4932437H03Rik; BM032; Cenpj; CENP-J; Centromere protein J; centrosomal P4.1-associated protein; CPAP; Gm81; LAG-3-associated protein; LAP; LIP1; LYST-interacting protein 1; LYST-interacting protein LIP1; LYST-interacting protein LIP7; MCPH6; microcephaly; Sas4; Sas-4; SASS4; SCKL4
• Gene Symbols: CENPJ
• Host Species: Mouse
• Immunogen: CENPJ (NP_060921, 979 a.a. ~ 1088 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Affinity Chromatography
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 55835
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a κ