CENPJ Monoclonal Antibody (OTI3G8), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA811852

Catalog No. 50-168-4291

Description

This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintece of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation.

Specifications

• Antigen: CENPJ
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: CENPJ
• Gene Alias: BM032, CENP-J, CPAP, LAP, LIP1, MCPH6, SASS4, SCKL4, Sas-4
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55835
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Clone: OTI3G8
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q9HC77
• Gene Symbols: CENPJ
• Immunogen: Human recombit protein fragment corresponding to amino acids 1087-1338 of human CENPJ produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a