Invitrogen™ CENPJ Polyclonal Antibody

Catalog No.	Quantity
PIPA5100718	100 μL

Catalog No. PIPA5100718 Supplier Invitrogen™ Supplier No. PA5100718

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CENPJ.

This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation.

Specifications

• Antigen: CENPJ
• Applications: Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: CENPJ
• Gene Accession No.: Q569L8, Q9HC77
• Gene Alias: 4932437H03Rik; BM032; Cenpj; CENP-J; Centromere protein J; centrosomal P4.1-associated protein; CPAP; Gm81; LAG-3-associated protein; LAP; LIP1; LYST-interacting protein 1; LYST-interacting protein LIP1; LYST-interacting protein LIP7; MCPH6; microcephaly; Sas4; Sas-4; SASS4; SCKL4
• Gene Symbols: CENPJ
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human CENPJ(Accession Q9HC77), corresponding to amino acid residues F1265-E1315.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 219103, 55835
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG