Invitrogen™ CENPJ Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550377

Catalog No. PA550377

Description

The antibody detects endogenous levels of total CENPJ protein.

This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation.

Specifications

• Antigen: CENPJ
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CENPJ
• Gene Alias: 4932437H03Rik; BM032; Cenpj; CENP-J; Centromere protein J; centrosomal P4.1-associated protein; CPAP; Gm81; LAG-3-associated protein; LAP; LIP1; LYST-interacting protein 1; LYST-interacting protein LIP1; LYST-interacting protein LIP7; MCPH6; microcephaly; Sas4; Sas-4; SASS4; SCKL4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55835
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1.8 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q9HC77
• Gene Symbols: CENPJ
• Immunogen: Fusion protein corresponding to residues near the C terminal of human centromere protein J.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG