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Invitrogen™ CENPJ Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550377

Catalog No. PA550377


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Description

Description

The antibody detects endogenous levels of total CENPJ protein.

This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CENPJ
Polyclonal
Unconjugated
CENPJ
4932437H03Rik; BM032; Cenpj; CENP-J; Centromere protein J; centrosomal P4.1-associated protein; CPAP; Gm81; LAG-3-associated protein; LAP; LIP1; LYST-interacting protein 1; LYST-interacting protein LIP1; LYST-interacting protein LIP7; MCPH6; microcephaly; Sas4; Sas-4; SASS4; SCKL4
Rabbit
Antigen affinity chromatography
RUO
55835
-20°C
Liquid
Immunohistochemistry (Paraffin)
1.8 mg/mL
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Q9HC77
CENPJ
Fusion protein corresponding to residues near the C terminal of human centromere protein J.
100 μL
Primary
Human
Antibody
IgG
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