Invitrogen™ CENPM Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA542854

Catalog No. PIPA542854

Description

Peptide sequence: CDLEVEGFRA TMAQRLVRVL QICAGHVPGV SALNLLSLLR SSEGPSLEDL Sequence homology: Cow: 79%; Dog: 79%; Horse: 93%; Human: 100%; Pig: 93%; Rabbit: 93%.

The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA replaces histone H3. CENPM is an additional factor required for centromere assembly.The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPM is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM].

Specifications

• Antigen: CENPM
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CENPM
• Gene Alias: 2610019I03Rik; AI853711; bK250D10.2; C22orf18; Cenpm; CENP-M; Centromere protein M; hypothetical protein LOC615953; ICEN39; Interphase centromere complex protein 39; MGC861; PANE1; proliferation associated nuclear element 1; proliferation-associated nuclear element protein 1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 79019
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9NSP4
• Gene Symbols: CENPM
• Immunogen: Synthetic peptide directed towards the middle region of human CENPM.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov