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Invitrogen™ CENPT Polyclonal Antibody
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Catalog No. PIPA563512
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100 μL
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PIPA563512 100 μL
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Catalog No. PIPA563512 Supplier Invitrogen™ Supplier No. PA563512
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PLHDGVEEAE KKMEEEGVSV SEMEATGAQG PSRVEEAEGH TEVTEAEGSQ GTAEADGPGA SSGDEDASGR AASPESASST PESLQARRHH QFLEP Highest antigen sequence identity to the following orthologs: Mouse - 31%, Rat - 34%.

Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPT has a fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most further proteins binding downstream. Required for normal chromosome organization and normal progress through mitosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CENPT
Applications ChIP Assay, Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CENPT
Gene Accession No. Q96BT3
Gene Alias C16orf56; CENPT; CENP-T; Centromere protein T; G630055P03Rik; ICEN22; Interphase centromere complex protein 22; RGD1309383
Gene Symbols CENPT
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CENPT. Recombinant protein control fragment (Product #RP-98620).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80152
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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