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Invitrogen™ Centrin 3 Polyclonal Antibody
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Catalog No. PIPA596938
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PIPA596938 100 μL
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Catalog No. PIPA596938 Supplier Invitrogen™ Supplier No. PA596938
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MSLALRSELV VDKTKRKKRR ELSEEQKQEI KDAFELFDTD KDEAIDYHEL KVAMRALGFD VKKADVLKIL KDYDREATGK ITFEDFNEVV TDWILERDPH EEILKAFKLF DDDDSGKISL RNLRRVAREL GENMSDEELR AMIEEFDKDG DGEINQEEFI AIMTGDI; Positive Samples: MCF-7, Jurkat, 293T, Mouse testis, Mouse spleen, Mouse lung, Mouse ovary; Cellular Location: Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center, nucleolus.

The protein encoded by this gene contains four EF-hand calcium binding domains, and is a member of the centrin protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae. Yeast CDC31 is located at the centrosome of interphase and mitotic cells, where it plays a fundamental role in centrosome duplication and separation. Multiple forms of the proteins similar to the yeast centrin have been identified in human and other mammalian cells, some of which have been shown to be associated with centrosome fractions. This protein appears to be one of the most abundant centrins associated with centrosome, which suggests a similar function to its yeast counterpart. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Centrin 3
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.54 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Cetn3
Gene Accession No. O15182, O35648
Gene Alias CDC31; CDC31 yeast homolog; CEN3; centrin 3; centrin, EF-hand protein, 3; centrin, EF-hand protein, 3 (CDC31 homolog, yeast); centrin-3; Cetn3; EF-hand superfamily member; MmCEN3
Gene Symbols Cetn3
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1070, 12626, 170895
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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