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Invitrogen™ CEP164 Polyclonal Antibody
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Catalog No. PIPA576461
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100 μL
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PIPA576461 100 μL
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Catalog No. PIPA576461 Supplier Invitrogen™ Supplier No. PA576461
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

CEP164 was initially identified as a centrosomal protein, but other studies have indicated that it also plays a role in the formation of primary cilia, the microtubule-based sensory antennae projecting from the surface of many eukaryotic cells as well as in DNA damage response acting as a mediator protein. CEP164 interacts with both ATR and ATM, proteins that trigger a number of cellular responses including the initiation of DNA damaged-induced cell cycle checkpoints. It is phosphorylated upon replication stress, ultraviolet (UV) radiation, and ionizing radiation silencing of CEP164 significantly reduces the DNA damage-induced phosphorylation of several proteins in the DNA damage-activated signaling cascade and compromises cell survival after UV damage. At least two isoforms of CEP164 are known to exist.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CEP164
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene CEP164
Gene Accession No. Q5DU05, Q9UPV0
Gene Alias AI450905; BC027092; ce164; centrosomal protein 164; centrosomal protein 164kDa; centrosomal protein of 164 kDa; Cep 164; CEP164; D030051D21; KIAA1052; mKIAA1052; NPHP15; RGD1560988; RGD1561243
Gene Symbols CEP164
Host Species Rabbit
Immunogen Recombinant fusion protein of human CEP164.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 214552, 22897, 363055
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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