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Invitrogen™ CEP290 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5101506
Description
Antibody detects endogenous levels of total CEP290.
This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.
Specifications
CEP290 | |
Polyclonal | |
Unconjugated | |
Cep290 | |
3H11Ag; b2b1454Clo; b2b1752Clo; Bardet-Biedl syndrome 14 protein; Bardet-Biedl syndrome 14 protein homolog; BBS14; BC004690; Cancer/testis antigen 87; centrosomal protein 290; centrosomal protein 290kDa; centrosomal protein of 290 kDa; Cep290; CT87; CTCL tumor antigen se2-2; JBTS5; Kiaa0373; LCA10; Meckel syndrome, type 4; MKS4; monoclonal antibody 3H11 antigen; nephrocystin-6; nephrocytsin-6; Nphp6; POC3; POC3 centriolar protein homolog; prostate cancer antigen T21; rd16; RGD1311640; SLSN6; tumor antigen se2-2 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
216274, 80184 | |
-20°C | |
Liquid |
Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
O15078, Q6A078 | |
Cep290 | |
A synthesized peptide derived from human CEP290(Accession O15078), corresponding to amino acid residues S779-E829. | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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