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Invitrogen™ CEP78 Polyclonal Antibody
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Catalog No. PIPA561823
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100 μL
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PIPA561823 100 μL
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Catalog No. PIPA561823 Supplier Invitrogen™ Supplier No. PA561823
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ALETNTTLVV LDIRKNPLID HSMMKAVIKK VLQNGRSAKS EYQWITSPSV KEPSKTAKQK RRTIILGSGH KGKATIRIGL ATKKPVSSGR K Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 84%.

This gene encodes a centrosomal protein that is both required for the regulation of centrosome-related events during the cell cycle, and required for ciliogenesis. The encoded protein has an N-terminal leucine-rich repeat (LRR) domain with six consecutive LRR repeats, and a C-terminal coiled-coil domain. It interacts with the N-terminal catalytic domain of polo-like kinase 4 (PLK4) and colocalizes with PLK4 to the distal end of the centriole. Naturally occurring mutations in this gene cause defects in primary cilia that result in retinal degeneration and sensorineural hearing loss which are associated with cone-rod degeneration disease as well as Usher syndrome. Low expression of this gene is associated with poor prognosis of colorectal cancer patients.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CEP78
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CEP78
Gene Accession No. Q5JTW2
Gene Alias 5730599I05Rik; C9orf81; centrosomal protein 78; centrosomal protein 78kDa; centrosomal protein of 78 kDa; Cep78; D030027P05; IP63
Gene Symbols CEP78
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CEP78. Recombinant protein control fragment (Product #RP-92996).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84131
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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