Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA5120751

Invitrogen™ Cerebral Protein 1 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA5120751
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA5120751 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Catalog No. PIPA5120751 Supplier Invitrogen™ Supplier No. PA5120751
Add to Cart
Add to Cart
This item is not returnable. View return policy

Description

Rabbit Polyclonal Antibody

Positive test controls include: Mouse kidney, Mouse spleen, Rat kidney, Rat thymus. Immunogen sequence: GPPCSDSEEE VERKKKCHKQ ALVGSDSAED EKRKRKCQKH APINSAQHLD NVDQTGPKAW KGSTTNDPPK QSPGSTSPKP PHTLSRKQWR NRQKNKRRCK N.

Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cerebral Protein 1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.104 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Rrp8
Gene Accession No. O43159, Q5U4F0, Q9DB85
Gene Alias 1500003O22Rik; 2900001K19Rik; AW538116; Cerebral protein 1; cerebral protein 1 homolog; HUCE1; hucep1; hucep-1; KIAA0409; NML; Nucleomethylin; RGD1308302; ribosomal RNA processing 8, methyltransferase, homolog (yeast); ribosomal RNA-processing protein 8; Rrp8; RRP-8; RRP8 methyltransferase homolog
Gene Symbols Rrp8
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 100-200 of human RRP8 (NP_056139.1).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 101867, 23378, 308911
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.