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Tocris™ Ceritinib

Highly potent ALK inhibitor; also potently inhibits IR, IGF1R, STK22D and FLT3

Manufacturer:  Tocris™ 6905/50

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Catalog No. 69-055-0


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Description

Description

Ceritinib is a highly potent anaplastic lymphoma kinase (ALK) inhibitor (IC50 = 0.2 nM). Also displays potent inhibition of insulin receptor (IR), insulin-like growth factor receptor 1 (IGF1R), serine/threonine-protein kinase STK22D and FLT3 (IC50 values are 7, 8, 23 and 60 nM, respectively). Inhibits tumor growth in Karpas299 and H2228 rat xenograft models.
Specifications

Specifications

C28H36ClN5O3S
558.14
LDK378
Highly potent ALK inhibitor; also potently inhibits IR, IGF1R, STK22D and FLT3
98%
50 mg
Safety and Handling

Safety and Handling

Recommended Storage : Store at 4°C

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