Invitrogen™ CERKL Polyclonal Antibody

Catalog No.	Quantity
PIPA5104531	100 μL

Catalog No. PIPA5104531

Supplier: Invitrogen™ PA5104531

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CERKL.

This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.[provided by RefSeq, May 2010].

Specifications

• Antigen: CERKL
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: CERKL
• Gene Accession No.: Q49MI3
• Gene Alias: ceramide kinase like; ceramide kinase-like; ceramide kinase-like protein; CERKL; Gm1958; retinitis pigmentosa 26 (autosomal recessive); Rp26; zgc:162213
• Gene Symbols: CERKL
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human CERKL(Accession Q49MI3), corresponding to amino acid residues L341-S391.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 228094, 375298
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

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