Invitrogen™ CERKL Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5115010

Catalog No. PIPA5115010

Description

Antibody detects endogenous levels of total CERKL.

This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.[provided by RefSeq, May 2010].

Specifications

• Antigen: CERKL
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CERKL
• Gene Alias: ceramide kinase like; ceramide kinase-like; ceramide kinase-like protein; CERKL; Gm1958; retinitis pigmentosa 26 (autosomal recessive); Rp26; zgc:162213
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 375298
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q49MI3
• Gene Symbols: CERKL
• Immunogen: A synthesized peptide derived from human CERKL(Accession Q49MI3), corresponding to amino acid residues L341-S391.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov