Invitrogen™ CES1 Monoclonal Antibody (3F10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA549209

Catalog No. PIMA549209

Description

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human THP-1 whole cell, human HEPG2 whole cell, rat liver tissue, mouse liver tissue. IHC: human liver cancer tissue, human tonsil tissue, human prostate cancer tissue, mouse lung tissue, rat liver tissue. ICC/IF: HEPG2 cell. Flow: HEPG2 cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.

Specifications

• Antigen: CES1
• Classification: Monoclonal
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and no preservative
• Gene Accession No.: P10959, P23141, P23953, Q63108, Q64176, Q8VCC2
• Gene Symbols: CES1, Ces1a, Ces1c, Ces1e, Ces1g
• Immunogen: E. coli-derived human Liver Carboxylesterase 1/CES1 recombinant protein (Position: E99-A206).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 3F10
• Conjugate: Unconjugated
• Gene: CES1
• Gene Alias: ACAT; acyl coenzyme A:cholesterol acyltransferase; acyl-coenzyme A:cholesterol acyltransferase; Brain carboxylesterase hBr1; carboxyesterase ES-3; carboxylesterase 1; carboxylesterase 1 (monocyte/macrophage serine esterase 1); carboxylesterase 1A; carboxylesterase 1E; Carboxylesterase 1G; carboxylesterase 1-like; carboxylesterase 2 (liver); CE-1; CEH; Ces1; Ces-1; Ces1a; Ces1e; Ces1g; Ces1l; CES2; cholesteryl ester hydrolase; cocaine carboxylesterase; Eg; EG244595; Egasyn; Es22; Es-22; ES-HTEL; esterase 22; esterase-22; ES-x; Gm4976; hCE-1; HMSE; HMSE1; human monocyte/macrophage serine esterase 1; liver carboxylesterase 1; Liver carboxylesterase 22; liver carboxylesterase 3; methylumbelliferyl-acetate deacetylase 1; MGC117365; Monocyte/macrophage serine esterase; PCE-1; pI 5.5 esterase; REH; Retinyl ester hydrolase; serine esterase 1; SES1; Ses-1; TGH; triacylglycero; Triacylglycerol hydrolase
• Host Species: Mouse
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1066, 12623, 13884, 13897, 24346, 244595, 29225, 679817
• Content And Storage: -20°C
• Form: Lyophilized