CFH Mouse anti-Human, Clone: OTI5H5, lyophilized, TrueMAB™

Catalog No.	Quantity
50-166-7024	100 μg

Catalog No. 50-166-7024 Supplier OriGene Supplier No. CF804532

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Complement factor H1 (Complement factor H1, factor H1, CFH) is a plasma glycoprotein (139 kDa) and the secreted form of the protein is composed of 20 repetitive units of 60 amino acids, named short consensus repeats (SCR). Factor H1 is a central regulator of early alternative pathway activation by acting as a cofactor for factor I in the cleavage of C3b into iC3b. Factor H1 also competes with factor B for binding with C3b, inhibiting excessive alternative pathway activation. Complete (homozygous) factor H1 deficiency by genetic mutation has been rarely reported.

Specifications

• Antigen: CFH
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI5H5
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: CFH
• Gene Accession No.: P08603
• Gene Alias: AHUS1, AMBP1, ARMD4, ARMS1, CFHL3, FH, FHL1, HF, HF1, HF2, HUS
• Gene Symbols: CFH
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 125-346 of human CFH produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3075
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG2b