Invitrogen™ CFHR1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120829

Catalog No. PIPA5120829

Description

Positive test controls include: LO2, HeLa, NCI-H460, Mouse liver, Mouse lung, Mouse heart, Rat liver. The target is usually found in the following locations: Secreted. Immunogen sequence: PTVQNAHILS RQMSKYPSGE RVRYECRSPY EMFGDEEVMC LNGNWTEPPQ CKDSTGKCGP PPPIDNGDIT SFPLSVYAPA SSVEYQCQNL YQLEGNKRIT CRNGQWSEPP KCLHPCVISR EIMENYNIAL RWTAKQKLYL RTGESAEFVC KRGYRLSSRS HTLRTTCWDG KLEYPTCAKR.

This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.

Specifications

• Antigen: CFHR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CFHR1
• Gene Alias: AI194696; CFHL; Cfhl1; CFHL1P; CFHR1; CFHR1P; CFHRB; complement component factor h-like 1; complement factor H related 1; complement factor H-related 1; complement factor H-related 1 pseudogene; complement factor H-related protein; complement factor H-related protein 1; FHR1; FHR-1; H factor (complement)-like 1; H factor (complement)-like 2; h factor-like protein 1; H36; H36-1; H36-2; H-factor-like 1; HFL1; HFL2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 289057, 3078, 50702
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 3.08 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q03591
• Gene Symbols: CFHR1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 151-330 of human CFHR1 (NP_002104.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG