Invitrogen™ CFHR4 Monoclonal Antibody (640212)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524288

Catalog No. PIMA524288

Description

In direct ELISAs, no cross-reactivity with recombinant human (rh) CFHR1, rhCFHR2, or rhCFHR5 is observed. Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.

This gene is a member of the complement factor H (CFH) gene family, and encodes one of the 5 CFH-related (CFHR) proteins. These 5 genes are closely linked to the CFH gene on chromosome 1q31-q32. The CFHRs are secreted plasma proteins synthesized primarily by the hepatocytes, and composed of highly-related short consensus repeats (SCRs). This protein enhances the cofactor activity of CFH, and is involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. Alternatively spliced transcript variants encoding different isoforms (varying in the number of SCRs) have been described for this gene.

Specifications

• Antigen: CFHR4
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q92496
• Gene Symbols: CFHR4
• Immunogen: Sf 21-derived recombinant human Complement Factor H-related 4/CFHR4 Glu20-Glu331.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: 640212
• Conjugate: Unconjugated
• Gene: CFHR4
• Gene Alias: CFHL4; CFHR4; complement factor H; complement factor H related 4; complement factor H-related 4; complement factor H-related protein 4; FHR4; FHR-4
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 10877
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized