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Invitrogen™ CFHR5 Monoclonal Antibody (3A10A5)
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Catalog No. PIMA531678
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100 μL
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Catalog No. Quantity
PIMA531678 100 μL
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Catalog No. PIMA531678 Supplier Invitrogen™ Supplier No. MA531678
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Description

Mouse Monoclonal Antibody

MA5-31678 has been tested in indirect ELISA.

This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS).
TRUSTED_SUSTAINABILITY

Specifications

Antigen CFHR5
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 3A10A5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene CFHR5
Gene Accession No. Q9BXR6
Gene Alias CFHL5; CFHR5; CFHR5D; complement factor H related 5; complement factor H-related 5; complement factor H-related protein 5; factor H-related protein 5; FHR5; FHR-5
Gene Symbols CFHR5
Host Species Mouse
Immunogen Purified recombinant fragment of human CFHR5 (AA: 344-569) expressed in E. coli.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 81494
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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