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CFLAR Mouse anti-Human, Clone: OTI2B9, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF804552

Encompass_Preferred

Catalog No. 50-166-7030


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

FLIP (CFLAR) is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.
Specifications

Specifications

CFLAR
Monoclonal
Unconjugated
CFLAR
CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS
Mouse
Affinity Chromatography
RUO
8837
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Western Blot
OTI2B9
PBS with 8% trehalose and no preservative; pH 7.3
O15519
CFLAR
Human recombit protein fragment corresponding to amino acids 1-272 of human CFLAR produced in E.coli.
100 μg
Primary
Human
Antibody
IgG3
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