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CFTR Rabbit anti-Human, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

$518.60

Specifications

Antigen CFTR
Concentration 0.37 mg/mL
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-173-3056
SDP
Encompass_Preferred
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Proteintech Group Inc
207381AP150UL
150 μL
Each of 1 for $518.60
Only null left
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Description

Description

Cystic Fibrosis (CF) is a common lethal genetic disease caused by mutations of the gene coding for the cystic fibrosis transmembrane conductance factor, a cAMP regulated chloride channel. Approximately 70% of all CF cases share the deletion of a phenylalanine at position 508 (delta F508) which results in abnormal chloride transport. Since the CF mutation is lethal, most often by lung and liver disease, it raises the question of why this genetic disease remains as common as it is. One possible explanation is that Salmonella typhi has been shown to use CFTR to enter intestinal epithelial cells and that delta F508 heterozygote and homozygote mice showed 86% and 100% reductions in S. typhi intestinal submucosal uptake.
Specifications

Specifications

CFTR
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Unconjugated
Rabbit
Human
P13569
1080
Peptide
Primary
-20°C
CFTR
0.37 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
ABC35, ABCC7, CF, CFTR, CFTR/MRP, MRP7, TNR CFTR
CFTR
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
Documents

Documents

Product Certifications
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