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Tocris Bioscience™ CFTRinh 172
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Catalog No. 343010
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Catalog No. Quantity
34-301-0 10 mg
34-305-0 50 mg
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Catalog No. 34-301-0 Supplier Tocris Bioscience™ Supplier No. 3430/10
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Description

Voltage-independent, selective CFTR chloride channel blocker

Voltage-independent, selective CFTR chloride channel blocker (Ki = 300 nM) that alters channel gating. Blocks intestinal fluid secretion induced by cholera toxin and Escherichia coli and suppresses cyst growth in animal models of polycystic kidney disease. Orally active. Inhibits mitochondrial respiration and increases reactive oxygen species (ROS) production independently of CFTR in several cell lines.

Chemical Identifiers

CAS 307510-92-5
Molecular Formula C18H10F3NO3S2

Specifications

Quantity 10 mg
Formula Weight 409.4
Purity >98%
Molecular Weight (g/mol) 409.397
Chemical Name or Material CFTRinh 172

Safety and Handling

Recommended Storage Store at +4°C
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