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Invitrogen™ cGKI Monoclonal Antibody (OTI9A4)
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Catalog No. PIMA525110
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Quantity:
100 μL
Catalog No. Quantity
PIMA525110 100 μL
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Catalog No. PIMA525110

Supplier: Invitrogen™ MA525110

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Mouse Monoclonal Antibody

cGKI Monoclonal Antibody for Western Blot, ICC/IF, Flow

PRKG1 is a cGMP-dependent serine/threonine kinase which has an important role in the relaxation of vascular smooth muscle and the inhibition of platelet aggregation. The PRKG1 proteins play a central role in regulating cardiovascular and neuronal functions in addition to relaxing smooth muscle tone, and modulating cell growth. This gene is most strongly expressed in all types of smooth muscle, platelets, cerebellar Purkinje cells, hippocampal neurons, and the lateral amygdala. Isoforms Ialpha and Ibeta have identical cGMP-binding and catalytic domains but differ in their leucine/isoleucine zipper and autoinhibitory sequences and therefore differ in their dimerization substrates and kinase enzyme activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen cGKI
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone OTI9A4
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PRKG1
Gene Accession No. Q13976
Gene Alias AAT8; AW125416; cGK; cGK 1; CGK 1 alpha; cGK 1 beta; cGK cGK cGKI; cGK cGK1; cGK1; cGKI; cGKI-alpha; cGKI-BETA; cGMP dependent protein kinase type 1; cGMP kinase type I alpha; cGMP-dependent protein kinase 1; cGMP-dependent protein kinase 1, alpha isozyme; cGMP-dependent protein kinase 1, beta isozyme; cGMP-dependent protein kinase I; Gm19690; OTTHUMP00000019618; PKG; Pkgi; Prkg1; PRKG1B; PRKGR1A; PRKGR1B; protein kinase cGMP-dependent 1; protein kinase, cGMP-dependent, regulatory, type I, beta; protein kinase, cGMP-dependent, type 1; protein kinase, cGMP-dependent, type I; RP11-346D6.1; Unknown (protein for MGC:134126); unnamed protein product
Gene Symbols PRKG1
Host Species Mouse
Immunogen Full length human recombinant protein of PRKG1 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5592
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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