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  5. Tocris Bioscience™ CGP 55845 hydrochloride

Tocris Bioscience™ CGP 55845 hydrochloride
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Catalog No. 124810
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Catalog No. Quantity
12-481-0 10 mg
12-485-0 50 mg
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Catalog No. 12-481-0 Supplier Tocris Bioscience™ Supplier No. 1248/10
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Description

Potent and selective GABAB antagonist

Potent, selective GABAB receptor antagonist (IC50 = 5 nM) that prevents agonist binding (pKi = 8.35) and inhibits GABA and glutamate release (pEC50 values are 8.08 and 7.85 respectively). Inhibits GABAB responses to baclofen (IC50 = 130 nM in an isoproterenol assay) and potentiates the hypoglycemic response to glucose in vitro.

Chemical Identifiers

CAS 149184-22-5
Molecular Formula C18H23Cl3NO3P

Specifications

Quantity 10 mg
Formula Weight 438.71
Purity >98%
Molecular Weight (g/mol) 438.71
Chemical Name or Material CGP 55845 hydrochloride

Safety and Handling

Recommended Storage Store at Room Temperature
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