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Tocris Bioscience™ CGP 60474
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Catalog No. 547110
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54-711-0 10 mg
54-715-0 50 mg
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Catalog No. 54-711-0 Supplier Tocris Bioscience™ Supplier No. 5471/10
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Description

Potent cdk inhibitor

CGP 60474 is a potent cyclin-dependent kinase (cdk) inhibitor (reported IC50 values are 3 - 80, 9.5, 13, 17 - 60, 200 and 220 nM for cdk2, cdk5, cdk9, cdk1, cdk4 and cdk7, respectively). Also inhibits PKCα in the low micromolar range. Displays reversible G1/S cell cycle arrest in U2-OS cells.

Specifications

Chemical Name or Material 3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol
CAS 164658-13-3
Quantity 10 mg
Target Cyclin-dependent Kinase Inhibitors
Molecular Formula C18H18ClN5O
Formula Weight 355.82
Purity >98%
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