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Tocris Bioscience™ CGP 60474

Potent cdk inhibitor

Supplier:  Tocris Bioscience™ 5471/50

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Catalog No. 54-715-0


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Description

Description

CGP 60474 is a potent cyclin-dependent kinase (cdk) inhibitor (reported IC50 values are 3 - 80, 9.5, 13, 17 - 60, 200 and 220 nM for cdk2, cdk5, cdk9, cdk1, cdk4 and cdk7, respectively). Also inhibits PKCα in the low micromolar range. Displays reversible G1/S cell cycle arrest in U2-OS cells.
Specifications

Specifications

3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol
50 mg
C18H18ClN5O
>98%
164658-13-3
Cyclin-dependent Kinase Inhibitors
355.82
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Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

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