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  5. Tocris Bioscience™ CGP 74514 dihydrochloride

Tocris Bioscience™ CGP 74514 dihydrochloride
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Catalog No. 547210
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Catalog No. Quantity
54-721-0 10 mg
54-725-0 50 mg
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Catalog No. 54-721-0 Supplier Tocris Bioscience™ Supplier No. 5472/10
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Description

Potent cdk1 inhibitor

CGP 74514 dihydrochloride is a potent cdk1 inhibitor (IC50 = 25 nM). Reduces Akt phosphorylation and increases mitochondrial damage in leukemia cells in vitro in combination with LY 294002 .

Specifications

Chemical Name or Material rel-N2-[(1R,2S)-2-Aminocyclohexyl]-N6-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine dihydrochloride
Quantity 10 mg
Target Cyclin-dependent Kinase Inhibitors
Molecular Formula C19H24ClN7.2HCl
Formula Weight 458.82
Purity >98%
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