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Invitrogen™ CGREF1 Polyclonal Antibody
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Catalog No. PIPA552536
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100 μL
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PIPA552536 100 μL
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Catalog No. PIPA552536 Supplier Invitrogen™ Supplier No. PA552536
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PKDGVTRPDS EVQHQLLPNP FQPGQEQLGL LQSYLKGLGR TEVQLEHLSR EQVLLYLFAL HDYDQSGQLD GLELLSMLTA ALAPGAANSP TTNPVILIVD KVLETQDLNG DGLMTPAELI NFPGVALRHV EPG Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 72%.

CGREF1 (cell growth regulator with EF-hand domain 1), also known as CGR11, is a 301 amino acid secreted protein that contains two highly conserved calcium binding EF-hand domains, which are required for mediating cell-cell adhesion. Induced by p53, CGREF1 is able to inhibit cell growth in various cell lines. CGREF1 is encoded by a gene located on human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstrom syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CGREF1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CGREF1
Gene Accession No. Q99674
Gene Alias 1110004G24Rik; AW045201; cell growth regulator with EF hand domain 1; cell growth regulator with EF hand domain protein 1; cell growth regulator with EF-hand domain 1; cell growth regulatory gene 11 protein; cell growth regulatory with EF-hand domain; CGR11; Cgref1; Hydrophobestin
Gene Symbols CGREF1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CGREF1. Recombinant protein control fragment (Product #RP-89919).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10669
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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