Invitrogen™ CGREF1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA580474

Catalog No. PIPA580474

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human CGREF1.

CGREF1 (cell growth regulator with EF-hand domain 1), also known as CGR11, is a 301 amino acid secreted protein that contains two highly conserved calcium binding EF-hand domains, which are required for mediating cell-cell adhesion. Induced by p53, CGREF1 is able to inhibit cell growth in various cell lines. CGREF1 is encoded by a gene located on human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstrom syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.

Specifications

• Antigen: CGREF1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CGREF1
• Gene Alias: 1110004G24Rik; AW045201; cell growth regulator with EF hand domain 1; cell growth regulator with EF hand domain protein 1; cell growth regulator with EF-hand domain 1; cell growth regulatory gene 11 protein; cell growth regulatory with EF-hand domain; CGR11; Cgref1; Hydrophobestin
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 10669
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: Q99674
• Gene Symbols: CGREF1
• Immunogen: Recombinant Human CGREF1 Protein (Met1-Ile301).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG