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  8. CH 223191, Tocris Bioscience™

CH 223191, Tocris Bioscience™

Catalog Number 385810
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
301326-22-7
C19H19N5O
333.395
LKTNEXPODAWWFM-UHFFFAOYSA-N
ahr antagonist, unii-hye7315z4c, 2-methyl-2h-pyrazole-3-carboxylic acid 2-methyl-4-o-tolylazo-phenyl-amide, 2-methyl-2h-pyrazole-3-carboxylic acid-2-methyl-4-o-tolyl-azophenyl-amide, 1-methyl-n-2-methyl-4-e-2-methylphenyl diazenyl phenyl-1h-pyrazole-5-carboxamide, 2-methyl-n-2-methyl-4-e-2-2-methylphenyl diazen-1-yl phenyl pyrazole-3-carboxamide, 2-methyl-n-2-methyl-4-2-2-methylphenyl diazen-1-yl phenyl pyrazole-3-carboxamide, 1h-pyrazole-5-carboxamide, 1-methyl-n-2-methyl-4-2-methylphenyl azo phenyl, 1h-pyrazole-5-carboxamide, 1-methyl-n-2-methyl-4-2-2-methylphenyl diazenyl phenyl, 1-methyl-n-2-methyl-4-2-2-methylphenyl diazenyl phen yl-1h-pyrazole-5-carboxamide
3091786
2-methyl-N-[2-methyl-4-[(2-methylphenyl)diazenyl]phenyl]pyrazole-3-carboxamide
CC1=CC=CC=C1N=NC2=CC(=C(C=C2)NC(=O)C3=CC=NN3C)C
This item is not returnable. View return policy
301326-22-7
C19H19N5O
333.395
LKTNEXPODAWWFM-UHFFFAOYSA-N
ahr antagonist, unii-hye7315z4c, 2-methyl-2h-pyrazole-3-carboxylic acid 2-methyl-4-o-tolylazo-phenyl-amide, 2-methyl-2h-pyrazole-3-carboxylic acid-2-methyl-4-o-tolyl-azophenyl-amide, 1-methyl-n-2-methyl-4-e-2-methylphenyl diazenyl phenyl-1h-pyrazole-5-carboxamide, 2-methyl-n-2-methyl-4-e-2-2-methylphenyl diazen-1-yl phenyl pyrazole-3-carboxamide, 2-methyl-n-2-methyl-4-2-2-methylphenyl diazen-1-yl phenyl pyrazole-3-carboxamide, 1h-pyrazole-5-carboxamide, 1-methyl-n-2-methyl-4-2-methylphenyl azo phenyl, 1h-pyrazole-5-carboxamide, 1-methyl-n-2-methyl-4-2-2-methylphenyl diazenyl phenyl, 1-methyl-n-2-methyl-4-2-2-methylphenyl diazenyl phen yl-1h-pyrazole-5-carboxamide
3091786
2-methyl-N-[2-methyl-4-[(2-methylphenyl)diazenyl]phenyl]pyrazole-3-carboxamide
CC1=CC=CC=C1N=NC2=CC(=C(C=C2)NC(=O)C3=CC=NN3C)C

Description

Potent aryl hydrocarbon receptor (AhR) antagonist

Potent aryl hydrocarbon receptor (AhR) antagonist (IC50 = 30 nM). Exhibits no AhR agonist-like activity (at concentrations up to 100 μM). Inhibits 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-induced AhR-dependent transcription in vitro and reduces TCDD-induced toxicity in vivo. Attenuates Th17 differentiation of naive CD4 T cells and promotes expansion of hematopoietic stem cells in vitro.
Quantity 10 mg
Formula Weight 333.39
Percent Purity >98%
Chemical Name or Material CH 223191

Safety and Handling

Recommended Storage Store at +4°C
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