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  5. Tocris Bioscience™ CH 223191

Tocris Bioscience™ CH 223191

Catalog No. 385810
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent aryl hydrocarbon receptor (AhR) antagonist

Potent aryl hydrocarbon receptor (AhR) antagonist (IC50 = 30 nM). Exhibits no AhR agonist-like activity (at concentrations up to 100 μM). Inhibits 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-induced AhR-dependent transcription in vitro and reduces TCDD-induced toxicity in vivo. Attenuates Th17 differentiation of naive CD4 T cells and promotes expansion of hematopoietic stem cells in vitro.

Chemical Identifiers

CAS 301326-22-7
Molecular Formula C19H19N5O

Specifications

Quantity 10 mg
Formula Weight 333.39
Purity >98%
Molecular Weight (g/mol) 333.395
Chemical Name or Material CH 223191

Safety and Handling

Recommended Storage Store at +4°C
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