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Chaetoglobosin A, Tocris Bioscience™

Catalog No. 58041
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Quantity:
1 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Antibiotic; selectively induces apoptosis of CLL cells

Antibiotic; preferentially induces apoptosis in chronic lymphocytic leukemia (CLL) cells over normal B cells. Inhibits actin polymerization and leads to the accumulation of cells in G2 phase.

Chemical Identifiers

CAS 50335-03-0
Molecular Formula C32H36N2O5
Molecular Weight (g/mol) 528.65
MDL Number MFCD08273781
InChI Key OUMWCYMRLMEZJH-VIRVUJSBSA-N
Synonym Chaetoglobosin A
PubChem CID 133554307
IUPAC Name (1R,3E,6R,7E,9S,11E,14S,16R,17S,18R,19S)-6-hydroxy-19-[(1H-indol-3-yl)methyl]-7,9,16,17-tetramethyl-15-oxa-20-azatetracyclo[11.8.0.0¹,¹⁸.0¹⁴,¹⁶]henicosa-3,7,11-triene-2,5,21-trione
SMILES C[C@H]1[C@H]2[C@H](CC3=CNC4=CC=CC=C34)NC(=O)[C@@]22C(\C=C\C[C@H](C)\C=C(C)\[C@@H](O)C(=O)\C=C\C2=O)[C@@H]2O[C@]12C

Specifications

Linear Formula C32H36N2O5
Quantity 1 mg
Solubility Information Soluble to 100mM in DMSO
Formula Weight 528.64
Percent Purity >98%
Physical Form Solid
Chemical Name or Material (1E,4S,5E,7R,9E,11aR,14S,14aR,15S,15aR,16aS,16bR)-4,7,14,14a,15,15a,16a,16b-Octahydro-7-hydroxy-14-(
Recommended Storage Store at −20°C
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