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CHAF1B Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501735723 Shop All Proteintech Group Inc Products
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50-173-5723 150 μL
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Catalog No. 50-173-5723 Supplier Proteintech Group Inc Supplier No. 276331AP150UL
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Rabbit Polyclonal Antibody

Cyclin E, one of the activators of the cyclin-dependent kinase Cdk2, is critical for the initiation of DNA replication and other S-phase functions. The proper timing and amplitude of cyclin E expression seem to be important, because elevated levels of cyclin E have been associated with a variety of maligcies and constitutive expression of cyclin E leads to genomic instability. Phosphorylated cyclin E depends on the novel human gene, hCdc4, that was found to be mutated in a cell line derived from breast cancer that expressed extremely high levels of cyclin E.

Specifications

Antigen CHAF1B
Applications Western Blot
Classification Polyclonal
Concentration 0.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene CHAF1B
Gene Accession No. Q13112
Gene Alias CAF 1, CAF 1 subunit B, CAF I 60 kDa subunit, CAF I p60, CAF IP60, CAF1, CAF1A, CAF1P60, CHAF1B, M phase phosphoprotein 7, MPHOSPH7, MPP7
Gene Symbols CHAF1B
Host Species Rabbit
Immunogen CHAF1B Fusion Protein Ag26504
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8208
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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