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Invitrogen™ CHD1L Polyclonal Antibody
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Catalog No. PIPA531440
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100 μL
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PIPA531440 100 μL
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Catalog No. PIPA531440 Supplier Invitrogen™ Supplier No. PA531440
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Rabbit Polyclonal Antibody

Recommended positive controls: 293T, HepG2, HepG2 nucleus. Predicted reactivity: Mouse (92%), Bovine (93%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1; MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).
TRUSTED_SUSTAINABILITY

Specifications

Antigen CHD1L
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1.02 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene CHD1L
Gene Accession No. Q86WJ1
Gene Alias 4432404A22Rik; ALC1; amplified in liver cancer 1; amplified in liver cancer protein 1; CHD1L; CHDL; chromodomain helicase DNA binding protein 1 like; chromodomain helicase DNA binding protein 1-like; chromodomain-helicase-DNA-binding protein 1-like; LOW QUALITY PROTEIN: chromodomain-helicase-DNA-binding protein 1-like; Snf2p; Unknown (protein for MGC:128792)
Gene Symbols CHD1L
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human CHD1L. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9557
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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