Invitrogen™ CHD1L Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531440

Catalog No. PIPA531440

Description

Recommended positive controls: 293T, HepG2, HepG2 nucleus. Predicted reactivity: Mouse (92%), Bovine (93%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1; MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).

Specifications

• Antigen: CHD1L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHD1L
• Gene Alias: 4432404A22Rik; ALC1; amplified in liver cancer 1; amplified in liver cancer protein 1; CHD1L; CHDL; chromodomain helicase DNA binding protein 1 like; chromodomain helicase DNA binding protein 1-like; chromodomain-helicase-DNA-binding protein 1-like; LOW QUALITY PROTEIN: chromodomain-helicase-DNA-binding protein 1-like; Snf2p; Unknown (protein for MGC:128792)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9557
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 1.02 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q86WJ1
• Gene Symbols: CHD1L
• Immunogen: Recombinant protein encompassing a sequence within the center region of human CHD1L. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG