Invitrogen™ CHD3 Monoclonal Antibody (2G4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515579

Catalog No. PIMA515579

Description

MA5-15579 targets CHD3 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human and mouse samples. The MA5-15579 immunogen is purified recombinant fragment of human CHD3 expressed in E. Coli. MA5-15579 detects CHD3 which has a predicted molecular weight of approximately 226kDa.

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

Specifications

• Antigen: CHD3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: Q12873
• Gene Symbols: CHD3
• Immunogen: Purified recombinant fragment of human CHD3 expressed in E. Coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 2G4
• Conjugate: Unconjugated
• Gene: CHD3
• Gene Alias: 2600010P09Rik; AF020312; ATP-dependent helicase CHD3; CG9594; CG9594-PA; CHD3; CHD-3; Chd3-PA; Chd7; chromodomain helicase DNA binding protein 3; chromodomain-helicase-DNA-binding protein 3; dCHD3; DmCHD3; Dmel\CG9594; Dmel_CG9594; hZFH; MGC40857; Mi 2a; Mi2 ALPHA; Mi-2 alpha; mi-2 autoantigen 240 kDa protein; Mi-2a; Mi2-alpha; Prp7; Prp9 1; Prp9-1; ZFH; Zinc finger helicase; zinc-finger helicase (Snf2-like)
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 1107, 216848
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

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