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CHD3 Monoclonal Antibody (7A11), Active Motif™
SDP

Catalog No. 501993427
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50-199-3427 10 μg
50-199-3426 100 μg
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Catalog No. 50-199-3427 Supplier Active Motif Supplier No. 61470
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Description

Rat Monoclonal Antibody

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

Specifications

Antigen CHD3
Applications Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 7A11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene CHD3
Gene Accession No. O16102
Gene Alias 2600010P09Rik; AF020312; ATP-dependent helicase CHD3; CHD3; CHD-3; Chd7; chromodomain helicase DNA binding protein 3; Chromodomain-helicase-DNA-binding protein 3; hZFH; MGC40857; Mi 2a; Mi2 ALPHA; Mi-2 alpha; Mi-2 autoantigen 240 kDa protein; Mi-2a; Mi2-alpha; Prp7; Prp9 1; Prp9-1; ZFH; Zinc finger helicase; zinc-finger helicase (Snf2-like)
Gene Symbols CHD3
Host Species Rat
Immunogen This antibody was raised against a synthetic peptide corresponding to amino acid residues 865-885 of Drosophila CHD3.
Purification Method Protein G
Quantity 10 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 40111
Target Species Drosophila
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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