Invitrogen™ CHD3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA567428

Catalog No. PIPA567428

Description

Immunogen sequence: PAPSEKGEGIR TPLEKEEAEN QEEKPEKNSR IGEKMETEAD APSPAPSLGE RLEPRKIPLE DEVPGVPGEM EPEPGYRGDR EKSATESTPG ERGEEKPLDG Highest antigen sequence identity to the following orthologs - mouse 82%, rat 81%.

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

Specifications

• Antigen: CHD3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHD3
• Gene Alias: 2600010P09Rik; AF020312; ATP-dependent helicase CHD3; CG9594; CG9594-PA; CHD3; CHD-3; Chd3-PA; Chd7; chromodomain helicase DNA binding protein 3; chromodomain-helicase-DNA-binding protein 3; dCHD3; DmCHD3; Dmel\CG9594; Dmel_CG9594; hZFH; MGC40857; Mi 2a; Mi2 ALPHA; Mi-2 alpha; mi-2 autoantigen 240 kDa protein; Mi-2a; Mi2-alpha; Prp7; Prp9 1; Prp9-1; ZFH; Zinc finger helicase; zinc-finger helicase (Snf2-like)
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1107
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q12873
• Gene Symbols: CHD3
• Immunogen: Recombinant Human CHD3. Recombinant protein control fragment (Product #RP-108089).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG