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Invitrogen™ CHD3 Recombinant Rabbit Monoclonal Antibody (8Z6L6)
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Catalog No. PIMA538159
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PIMA538159 100 μL
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Catalog No. PIMA538159 Supplier Invitrogen™ Supplier No. MA538159
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Rabbit Recombinant Monoclonal Antibody

Positive Samples: HeLa, Jurkat, Mouse brain, Rat brain Immunogen sequence: MKAADTVILW ARSKNDQLRI SFPPGLCWGD RMPDKDDIRL LPSALGVKKR KRGPKKQKEN KPGKPRKRKK RDSEEEFGSE RDEYREKSES GGSEYGTGPG.

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CHD3
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 8Z6L6
Concentration 1.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.05% BSA and 0.02% sodium azide; pH 7.3
Gene CHD3
Gene Accession No. Q12873
Gene Alias 2600010P09Rik; AF020312; ATP-dependent helicase CHD3; CG9594; CG9594-PA; CHD3; CHD-3; Chd3-PA; Chd7; chromodomain helicase DNA binding protein 3; chromodomain-helicase-DNA-binding protein 3; dCHD3; DmCHD3; Dmel\CG9594; Dmel_CG9594; hZFH; MGC40857; Mi 2a; Mi2 ALPHA; Mi-2 alpha; mi-2 autoantigen 240 kDa protein; Mi-2a; Mi2-alpha; Prp7; Prp9 1; Prp9-1; ZFH; Zinc finger helicase; zinc-finger helicase (Snf2-like)
Gene Symbols CHD3
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1107, 216848, 303241
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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