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Tocris Bioscience™ Chelerythrine chloride
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Catalog No. 13305
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13-305 5 mg
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Catalog No. 13-305 Supplier Tocris Bioscience™ Supplier No. 1330/5
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Description

Cell-permeable protein kinase C inhibitor

Cell-permeable inhibitor of protein kinase C (IC50 = 660 nM); competitive with respect to the phosphate acceptor and non-competitive with respect to ATP. Has a wide range of biological activities, including antiplatelet, anti-inflammatory, antibacterial and antitumor effects. Activates MAPK pathways, independent of PKC inhibition. Inhibits binding of BclXL to Bak (IC50 = 1.5 μM) or Bad proteins and stimulates apoptosis.

Chemical Identifiers

CAS 3895-92-9
Molecular Formula C21H18ClNO4

Specifications

Quantity 5 mg
Formula Weight 383.83
Purity >98%
Molecular Weight (g/mol) 383.83
Chemical Name or Material Chelerythrine chloride

Safety and Handling

Recommended Storage Desiccate at -20°C
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