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Invitrogen™ Chemerin Monoclonal Antibody (D2), Invitrogen™
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Catalog No. FEMA550909
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200 μL
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FEMA550909 200 μL
FEMA550910 20 μL
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Catalog No. FEMA550909 Supplier Invitrogen™ Supplier No. MA550909
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Description

Mouse Monoclonal Antibody

Retinoids act through ligand-dependent transcription factors, retinoid X receptor (RXRs) and retinoic acid receptors (RARs). Tazarotene-induced gene (TIG) proteins, also designated retinoic acid receptor responder proteins or RAR-responsive proteins, can be membrane bound or secreted. TIGs act as tumor suppressor genes in human cancers and are highly expressed in skin, hair follicles and endothelial cells as well as in pancreas, spleen and intestine. TIGs are activated by tazarotene and have been implicated as growth regulators that mediate the growth suppressive effects of retinoids. TIG2 is a secreted protein that is mainly expressed in epidermis, hair follicles and endothelial cells. TIG2 is inhibited in psoriatic lesions and is activated by tazarotene in skin rafts and in epidermis of psoriatic lesions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Chemerin
Applications Western Blot
Classification Monoclonal
Clone D2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
Gene Rarres2
Gene Alias 0610007L05Rik; AI303516; Chemerin; HP10433; Rarres2; RAR-responsive protein TIG2; retinoic acid receptor responder (tazarotene induced) 2; retinoic acid receptor responder 2; retinoic acid receptor responder protein 2; Tazarotene-induced gene 2 protein; TIG2; TIG-2; TIG2HP10433
Gene Symbols Rarres2
Host Species Mouse
Immunogen Recombinant Rat CHEM protein, Ser25-Gly152 (Accession #Q5BK77).
Purification Method Protein A/G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 297073
Target Species Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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