Invitrogen™ Chemerin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121049

Catalog No. PIPA5121049

Description

Positive test controls include: 293T, BT-474, HeLa, Mouse liver. The target is usually found in the following locations: Secreted. Immunogen sequence: VGVAELTEAQ RRGLQVALEE FHKHPPVQWA FQETSVESAV DTPFPAGIFV RLEFKLQQTS CRKRDWKKPE CKVRPNGRKR KCLACIKLGS EDKVLGRLVH CPIETQVLRE AEEHQETQCL RVQRAGEDPH SFYFPGQFAF SKALPRS.

Retinoids act through ligand-dependent transcription factors, retinoid X receptor (RXRs) and retinoic acid receptors (RARs). Tazarotene-induced gene (TIG) proteins, also designated retinoic acid receptor responder proteins or RAR-responsive proteins, can be membrane bound or secreted. TIGs act as tumor suppressor genes in human cancers and are highly expressed in skin, hair follicles and endothelial cells as well as in pancreas, spleen and intestine. TIGs are activated by tazarotene and have been implicated as growth regulators that mediate the growth suppressive effects of retinoids. TIG2 is a secreted protein that is mainly expressed in epidermis, hair follicles and endothelial cells. TIG2 is inhibited in psoriatic lesions and is activated by tazarotene in skin rafts and in epidermis of psoriatic lesions.

Specifications

• Antigen: Chemerin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rarres2
• Gene Alias: 0610007L05Rik; AI303516; Chemerin; HP10433; Rarres2; RAR-responsive protein TIG2; retinoic acid receptor responder (tazarotene induced) 2; retinoic acid receptor responder 2; retinoic acid receptor responder protein 2; Tazarotene-induced gene 2 protein; TIG2; TIG-2; TIG2HP10433
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5919, 71660
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 0.57 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: Q99969, Q9DD06
• Gene Symbols: Rarres2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 17-163 of human RARRES2 (NP_002880.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG