Chenodeoxycholic acid, Thermo Scientific Chemicals

Description

Bile acid that induces apoptosis through protein kinase C signaling pathways

Chenodeoxycholic acid is a bile acid that induces apoptosis through protein kinase C signaling pathways.Chenodeoxycholic acid is widely utilized in therapeutic applications. It is applied in medical therapy to dissolve gallstones. It is employed in the treatment of cerebrotendineous xanthomatosis. It is used to treat constipation and cerebrotendineous xanthomatosis. It acts as a urea receptor in supramolecular chemistry which can contain anions. It is a staining additive commonly used with ruthenium or organic photo-sensitizers in the preparation of staining solutions for dye solar cells.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water, dimethyl sulfoxide, ethanol and dimethylformamide.

Notes
Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 474-25-9
• Molecular Formula: C24H40O4
• Molecular Weight (g/mol): 392.58
• MDL Number: MFCD00064142
• InChI Key: RUDATBOHQWOJDD-BSWAIDMHSA-N
• Synonym: chenodexycholic acid, chenodeoxycholate anion, chenodeoxycholate 1-, 3alpha, 7alpha-dihydroxy-5beta-cholanic acid, 3alpha,7alpha-dihydroxy-5beta-cholan-24-oate, 3alpha,7alpha-dihydroxy-5beta-cholan-24-oic acid anion, 4r-4-3r,5s,7r,8r,9s,10s,13r,14s,17r-10,13-dimethyl-3,7-bis oxidanyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta a phenanthren-17-yl pentanoate, 4r-4-3r,5s,7r,8r,9s,10s,13r,14s,17r-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta a phenanthren-17-yl pentanoate
• PubChem CID: 9548590
• ChEBI: CHEBI:36234
• IUPAC Name: (4R)-4-[(1R,3aS,3bR,4R,5aS,7R,9aS,9bS,11aR)-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid
• SMILES: [H][C@@]12CC[C@H]([C@H](C)CCC(O)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])[C@H](O)C[C@]2([H])C[C@H](O)CC[C@]12C

• Melting Point: 164°C to 168°C
• Color: White
• Quantity: 5 g
• Beilstein: 3219887
• Merck Index: 14,2054
• Solubility Information: Soluble in water,dimethyl sulfoxide,ethanol and dimethylformamide.
• Optical Rotation: +12° (c=2 in Ethanol)
• Formula Weight: 392.57
• Physical Form: Crystalline Needles
• Chemical Name or Material: Chenodeoxycholic acid

Safety and Handling

Hazard Category	H315-H319
Hazard Statement	GHS H Statement H361 Suspected of damaging fertility or the unborn child.
Precautionary Statement	P264b-P280-P302+P352-P305+P351+P338-P332+P313-P362-P501c
EINECSNumber	207-481-8
RTECSNumber	FZ1980000
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only