Invitrogen™ CHI3L1 Polyclonal Antibody

Sheep Polyclonal Antibody

Supplier:  Invitrogen™ PA547363

Catalog No. PIPA547363

Description

In Western blots, approximately 10% cross-reactivity with recombinant human Chitinase 3-like 1 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Human cartilage glycoprotein 39 (GP-39), also known as YKL-40, is a glycoprotein secreted by articular chondrocytes, synoviocytes and macrophages. Serum and synovial fluid GP-39 levels are elevated in inflammatory diseases and correlate with the degree of joint destruction in rheumatoid arthritis. GP-39 is expressed in articular chondrocytes and synovial cells, as well as in liver, but is undetectable in muscle tissues, lung, pancreas, mononuclear cells and fibroblasts. GP-39 is a candidate autoantigen in rheumatoid arthritis and is important in the capacity of cells to respond to and cope with changes in their environment.

Specifications

• Antigen: CHI3L1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Chil1
• Gene Alias: 38 kDa heparin-binding glycoprotein; 38kDa heparin-binding glycoprotein; 39 kDa synovial protein; 39 kDa whey protein; 40 kDa secretory signalling glycoprotein; ASRT7; AW208766; BP40; BP40 precursor; breast regression protein 39; Brp39; BRP39 protein; Cartilage glycoprotein 39; cartilage glycoprotein-39; CGP39; CGP-39; CHI3L1; Chil1; chitinase 3 like 1; Chitinase 3 like protein 1CGP 39; chitinase 3-like 1; chitinase 3-like 1 (cartilage glycoprotein-39); chitinase 3-like 1 protein; chitinase-3-like protein 1; chitinase-like 1; chitinase-like protein 1; CLP-1; DKFZp686N19119; FLJ38139; GP38K; Gp39; GP-39; hCGP39; HC-gp39; hCGP-39; HCGP-3P; Mammary gland protein 40; MGP-40; signal processing protein; signal-processing protein; SPC-40; SPS-40; YKL40; YKL-40; YYL-40
• Host Species: Sheep
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12654
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunoprecipitation, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q61362
• Gene Symbols: Chil1
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Chitinase 3-like 1 Tyr22-Ala381.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG