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Invitrogen™ CHI3L1 Recombinant Rabbit Monoclonal Antibody (7T1R3)
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Catalog No. FEMA551223
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100 μL
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FEMA551223 100 μL
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Catalog No. FEMA551223 Supplier Invitrogen™ Supplier No. MA551223
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: PGRFTKEAGT LAYYEICDFL RGATVHRILG QQVPYATKGN QWVGYDDQES VKSKVQYLKD RQLAGAMVWA LDLDDFQGSF CGQDLRFPLT NAIKDALAAT.

Human cartilage glycoprotein 39 (GP-39), also known as YKL-40, is a glycoprotein secreted by articular chondrocytes, synoviocytes and macrophages. Serum and synovial fluid GP-39 levels are elevated in inflammatory diseases and correlate with the degree of joint destruction in rheumatoid arthritis. GP-39 is expressed in articular chondrocytes and synovial cells, as well as in liver, but is undetectable in muscle tissues, lung, pancreas, mononuclear cells and fibroblasts. GP-39 is a candidate autoantigen in rheumatoid arthritis and is important in the capacity of cells to respond to and cope with changes in their environment.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CHI3L1
Applications ELISA, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 7T1R3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene CHI3L1
Gene Accession No. P36222, Q61362
Gene Alias 38 kDa heparin-binding glycoprotein; 38kDa heparin-binding glycoprotein; 39 kDa synovial protein; 39 kDa whey protein; 40 kDa secretory signalling glycoprotein; ASRT7; AW208766; BP40; BP40 precursor; breast regression protein 39; Brp39; BRP39 protein; Cartilage glycoprotein 39; cartilage glycoprotein-39; CGP39; CGP-39; CHI3L1; Chil1; chitinase 3 like 1; Chitinase 3 like protein 1CGP 39; chitinase 3-like 1; chitinase 3-like 1 (cartilage glycoprotein-39); chitinase 3-like 1 protein; chitinase-3-like protein 1; chitinase-like 1; chitinase-like protein 1; CLP-1; DKFZp686N19119; FLJ38139; GP38K; Gp39; GP-39; hCGP39; HC-gp39; hCGP-39; HCGP-3P; Mammary gland protein 40; MGP-40; signal processing protein; signal-processing protein; SPC-40; SPS-40; YKL40; YKL-40; YYL-40
Gene Symbols CHI3L1, Chil1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 284-383 of human YKL-40/CHI3L1 (NP_001267.2).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1116, 12654
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG
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