APP, Chicken, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-130-567	100 μg

Catalog No. 89-130-567 Supplier Abnova Corporation Supplier No. PAB29064

Description

Chicken polyclonal antibody raised against recombinant APP.

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq

Sequence: DAEFRHDSGYEVHHQKL

Specifications

• Antigen: APP
• Applications: Immunocytochemistry, Immunohistochemistry
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Chicken polyclonal antibody raised against recombinant APP.
• Dilution: Immunocytochemistry Immunohistochemistry The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.2 (0.02% sodium azide)
• Gene: APP
• Gene Alias: AAA/ABETA/ABPP/AD1/APPI/CTFgamma/CVAP/PN2
• Gene Symbols: APP
• Host Species: Chicken
• Immunogen: A KLH-conjugated synthetic peptide corresponding to residues 1-17 of the amyloid-beta peptide.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 351
• Target Species: Human
• Content And Storage: Store at 4°C and avoid from light.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgY

For Research Use Only