PML, Chicken, Biotin, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-129-487	50 μg

Catalog No. 89-129-487 Supplier Abnova Corporation Supplier No. PAB27972

Description

Chicken polyclonal antibody against synthetic peptide of PML

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Sequence: APASEEEFQFLR

Specifications

• Antigen: PML
• Applications: Immuno-MRM (Multiple Reaction Monitoring)
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Biotin
• Description: Chicken polyclonal antibody against synthetic peptide of PML
• Formulation: In Phosphate-Buffered Saline with 0.02% Sodium Azide.
• Gene: PML
• Gene Alias: MYL/PP8675/RNF71/TRIM19
• Gene Symbols: PML
• Host Species: Chicken
• Immunogen: A Synthetic peptide corresponding to amino acids of PML
• Purification Method: Antigen affinity purification
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5371
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage aliquot and store at -20°C. Avoid repeated freezing and thawing cycles.
• Form: Liquid
• Isotype: IgY

For Research Use Only