STAT3, Chicken, Biotin, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-129-499	20 μg

Catalog No. 89-129-499 Supplier Abnova Corporation Supplier No. PAB27984

Description

Chicken polyclonal antibody against synthetic phosphopeptide of STAT3

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq

Sequence: FICVTPTTCSNTIDLPM(pS)PR

Specifications

• Antigen: STAT3
• Applications: Immuno-MRM (Multiple Reaction Monitoring)
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Biotin
• Description: Chicken polyclonal antibody against synthetic phosphopeptide of STAT3
• Formulation: In Phosphate-Buffered Saline with 0.02% Sodium Azide.
• Gene: STAT3
• Gene Alias: APRF/FLJ20882/HIES/MGC16063
• Gene Symbols: STAT3
• Host Species: Chicken
• Immunogen: Synthetic phosphopeptide corresponding to amino acids of STAT3
• Purification Method: Antigen affinity purification
• Quantity: 20 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6774
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage aliquot and store at -20°C. Avoid repeated freezing and thawing cycles.
• Form: Liquid
• Isotype: IgY

For Research Use Only